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Mar , 2024

March , 2024:

RESEARCH HIGHLIGHTS

Activation of monomeric mechanosensitive ion channel TEMEM63

Wuqiang ZHAN

TMEM63s protein was identified as mechanically activated (MA) ion channels only recently, and play critical roles in normal central nervous system development and neurodegenerative diseases. Here, Zheng et al. solved the cryo-EM structure of HsTMEM63B and HsTMEM63B in uniquely monomeric configuration, wher...


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